PRF therapy in dentistry refers to the clinical use of Platelet-Rich Fibrin, a biological preparation derived entirely from the patient’s own blood, in dental and oral surgical procedures. It is a second-generation platelet concentrate that has been adopted in a range of dental specialties, including oral surgery, implantology, and periodontics.
This article explains what PRF is, how it differs from PRP, where it is used in dental practice, how it is prepared, and what products Revital Medica supplies to dental clinics.
What Is PRF and How Does It Differ from PRP?
PRF, Platelet-Rich Fibrin, belongs to the same family of autologous blood concentrates as PRP, but it is produced differently. Unlike PRP, PRF does not require anticoagulants or chemical activating agents during preparation. The blood sample is centrifuged without additives, and the natural clotting process is allowed to proceed. This produces a fibrin clot, a three-dimensional scaffold rich in platelets, growth factors, and white blood cells.
The resulting product can be used as a membrane, placed directly into a surgical site, or compressed into a gel. This makes it particularly suited to surgical applications where a physical scaffold is needed, rather than an injectable liquid.
PRP, by contrast, is typically prepared as a liquid and administered by injection. Both are derived from the patient’s own blood, and both involve platelet concentration, but their physical form and application method differ considerably.
Where Is PRF Used in Dental Practice?
PRF has been incorporated into a variety of dental and oral surgery procedures. The most common applications include:
- Post-extraction socket management — PRF membranes are placed into the socket after tooth extraction to support the healing process and reduce the risk of complications such as dry socket.
- Dental implant surgery — PRF is used around implant sites to support osseointegration and soft tissue healing. It can be placed in the socket before or alongside the implant.
- Sinus lift procedures — PRF is used as a biological membrane or mixed with bone graft materials in maxillary sinus augmentation.
- Bone grafting — PRF is combined with grafting materials to support bone regeneration in deficient areas.
- Periodontal surgery — PRF is used in procedures targeting bone and soft tissue defects around the teeth.
- Ridge preservation — following extraction, PRF can be used to preserve the shape and volume of the alveolar ridge before implant placement.
How Is PRF Prepared?
The preparation process takes place chairside, within the dental practice, during the patient’s appointment. A blood sample is drawn from the patient, typically from the arm, and placed immediately into a PRF-specific tube. The tube is loaded into a centrifuge and spun according to a defined protocol, usually at a lower speed and for a shorter duration than PRP preparation.
The centrifugation process causes the blood to separate into three layers: a red blood cell layer at the bottom, a fibrin clot (the PRF) in the middle, and a serum layer at the top. The practitioner removes the fibrin clot and compresses it if needed to produce a membrane of the desired density and thickness.
The entire process takes approximately eight to twelve minutes and can be performed while the patient is being prepared for surgery.
What Are the Advantages of a Chairside Preparation Process?
Because PRF is prepared from the patient’s blood in the dental chair immediately before use, there is no storage requirement and no transport of biological material. The product is fresh and used within minutes of preparation. This simplifies logistics considerably compared with externally prepared biological products.
The autologous nature of PRF also means that there is no risk of allergic reaction to the platelet concentrate itself, as it comes from the patient’s own body.
Ycellbio PRF Kits from Revital Medica
Revital Medica supplies Ycellbio PRF kits for use in PRF dental procedure settings across Europe. The kits are designed for consistent membrane production using standard centrifuge equipment, and do not require a dedicated centrifuge model.
Dental practices incorporating platelet rich fibrin dentistry protocols into their surgical workflow will find full product specifications, kit contents, and ordering information on the Revital Medica website.
Oral surgeons and implantologists using PRF oral surgery techniques can contact Revital Medica directly to discuss their clinical requirements and kit volumes.
Clinics seeking a reliable dental PRF kit supplier with European distribution and clinical support are welcome to reach out to the Revital Medica team.